Static and dynamic responses of carotid sinus baroreceptors in dogs with chronic volume overload.
نویسندگان
چکیده
منابع مشابه
Carotid sinus baroreceptors modulate tracheal smooth muscle tension in dogs.
Arterial baroreceptors are known to influence airway smooth muscle tone. Thus, increasing carotid sinus pressure from 20 to 200 mm Hg causes reflex tracheal dilation. However, the effects of changing sinus pressure around a normal arterial pressure set-point of 100 mm Hg have not been examined. In anesthetized, artificially ventilated dogs, we distended the vascularly isolated carotid sinuses w...
متن کاملExcitability of Carotid Sinus Baroreceptors
In this study we examined the effects of blockade of a transient K' current with 4aminopyridine (4-AP) on the static stimulus-response relation of myelinated carotid sinus baroreceptors (n=8), using a vascularly isolated sinus preparation in sodium thiopentalanesthetized dogs. In one class of baroreceptors (type I), which did not fire spontaneously below the pressure threshold (Pth), 4-AP (10-5...
متن کاملReflex effects of stimulation of carotid sinus and aortic baroreceptors on hindlimb vascular resistance in dogs.
Two series of experiments were performed on anesthetized dogs whose hindlimbs were perfused at constant flow and the blood pressures in the femoral artery, aortic arch, and carotid sinus recorded. The reflex changes in hindlimb vascular resistance were determined in response to changes in pressure in the aortic arch in the first series, and in the carotid sinus in the second. In each series, wh...
متن کاملChronic localized hypotension and resetting of carotid sinus baroreceptors. Electrophysiological and histological studies in the dog.
Resetting of carotid sinus (CS) baroreceptors to chronically elevated systemic pressure in hypertension has been demonstrated. The effects of chronic system hypotension on CS baroreceptor afferents has not been elucidated, however. The purpose of the present study was to determine the electrophysiological and histological characteristics of CS baroreceptors exposed to chronic hypotension. Chron...
متن کاملChronic Carotid Sinus Compression in Dogs: A Study of Hemodynamic Changes with and without Sinus Denervation
• Wakerlin and his associates have reported' 2 that chronic bilateral carotid sinus compression in dogs resulted in a sustained elevation of the mean arterial pressure. This finding was confirmed by Hawthorne and Gaspar, who reported also that the elevated mean arterial pressure after bilateral carotid sinus compression was ameliorated by hypophysectomy. Kezdi reported that bilateral constricti...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1985
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1985.sp015902